Lysergic Acid Diethylamide

Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug that was first synthesized in 1938 by Swiss chemist Albert Hofmann. LSD is derived from the fungus ergot, which grows on grains such as rye. It is classified as a Schedule I controlled substance in the United States, meaning it has a high potential for abuse and no accepted medical use.

LSD is typically taken orally in small doses, typically ranging from 20 to 80 micrograms. The effects of LSD can last for up to 12 hours, depending on the dose and individual tolerance. Some users report experiencing altered perceptions of reality, such as visual distortions, synesthesia (merging of senses), and feelings of euphoria or anxiety.

The mechanism of action of LSD is not fully understood, but it is believed to work primarily by binding to serotonin receptors in the brain. This alters the activity of certain neural circuits, leading to changes in perception, mood, and thought patterns.

While LSD is not considered physically addictive, it can be psychologically habit-forming, particularly in individuals who use it frequently or in high doses. It can also cause long-lasting changes in perception and cognition, a condition known as Hallucinogen Persisting Perception Disorder (HPPD). In rare cases, LSD use can also trigger acute psychosis or other psychiatric disorders.

Overall, LSD is a powerful and potentially dangerous drug that should only be used under medical supervision in very specific contexts, such as research into its therapeutic potential for treating certain mental health conditions.