What Is The Mechanism Of Action Of Aluminium Chloride Hexahydrate?

Aluminum chloride hexahydrate is a topical antiperspirant agent that works by blocking the eccrine sweat gland ducts in the skin.

When applied to the skin, aluminum chloride hexahydrate forms complexes with the proteins in the sweat gland ducts, causing them to become blocked. This reduces the amount of sweat that is released from the sweat glands onto the skin surface, which can help to control excessive sweating (hyperhidrosis).

In addition to its antiperspirant effects, aluminum chloride hexahydrate also has an astringent effect on the skin, which can help to reduce inflammation and irritation.

Overall, the mechanism of action of aluminum chloride hexahydrate involves blocking the sweat gland ducts and reducing the amount of sweat released from the skin surface, as well as providing astringent properties that can help to soothe and protect the skin.